Ozempic vs Saxenda: Comparing GLP-1 Weight Loss Options
Verdict Summary
Ozempic (semaglutide) produces significantly greater weight loss than Saxenda (liraglutide) and requires only once-weekly dosing vs daily. Saxenda has a longer track record in obesity specifically.
Medical Disclaimer: This comparison is for educational purposes only. Consult a healthcare provider before starting any peptide protocol. Full disclaimer →
At a Glance
| Dimension | Ozempic | Saxenda |
|---|---|---|
| Active Compound | Semaglutide | Liraglutide |
| Dosing Frequency | Once weekly | Once daily |
| Avg. Weight Loss | ~15% body weight | ~8% body weight |
| Administration | Subcutaneous injection | Subcutaneous injection |
| Cost | ~$900/month | ~$1,300/month |
Ozempic Deep Dive
Semaglutide has a longer half-life than liraglutide, enabling once-weekly dosing. The STEP trials demonstrated ~15% average weight loss at the 2.4mg Wegovy dose, significantly outperforming liraglutide in head-to-head studies.
How to Choose
Choose Ozempic if…
- •You want maximum weight loss efficacy
- •Weekly dosing convenience is important
- •Cost per unit of weight loss matters
Choose Saxenda if…
- •Daily dosing flexibility is preferred
- •You want the longest-established obesity-specific GLP-1
- •You have had adverse reactions to semaglutide
Frequently Asked Questions
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